{"id":13810,"date":"2018-11-12T09:15:17","date_gmt":"2018-11-12T09:15:17","guid":{"rendered":"http:\/\/faceinews.com\/?p=13810"},"modified":"2018-11-12T09:15:17","modified_gmt":"2018-11-12T09:15:17","slug":"dr-mohans-diabetes-announces-formation-of-national-monogenic-diabetes-study-group-of-india-on-the-occasion-of-world-diabetes-day","status":"publish","type":"post","link":"https:\/\/www.faceinews.com\/?p=13810","title":{"rendered":"Dr. Mohan\u2019s Diabetes announces formation of \u2018National Monogenic Diabetes Study Group of India\u2019 on the occasion of World Diabetes Day"},"content":{"rendered":"

\"Photo<\/a><\/strong>\u00a0<\/em><\/p>\n

This move highlights the importance of evaluating Monogenic Diabetes<\/p>\n

\u00a0\"Faceinews<\/a><\/em><\/strong><\/p>\n

Chennai, November, 2018 : <\/strong>As part of the World Diabetes Day 2018, <\/strong>Dr. Mohan\u2019s Diabetes Specialities Centre (DMDSC) conducted, a first of its kind press conference in Chennai to create awareness on the various forms of Monogenic Diabetes. Young patients with diabetes who are successfully undergoing treatment were also present at the conference to share their experience and educate the gathering on the importance of accurately diagnosing these relatively rare forms of diabetes known as \u2018Monogenic Diabetes\u2019. DMDSC <\/strong>and its sister institution Madras Diabetes Research Foundation (MDRF)<\/strong> also announced the formation of the National Monogenic Diabetes Study Group of India. <\/strong><\/p>\n

\u00a0<\/strong><\/p>\n

The two most common forms of diabetes are type 2 diabetes and type 1 diabetes. Both of these are polygenic disorders which means that several genes are involved and in addition, environmental factors also play a very important role in their etiology.<\/p>\n

\u00a0\"Photo<\/a><\/strong><\/p>\n

In contrast, Monogenic Diabetes <\/strong>is a group of disorders where mutation of a single gene<\/em> causes these forms of diabetes. \u00a0The 3 commonest forms of monogenic diabetes are 1) Maturity Onset Diabetes of the Young (MODY), 2) Neonatal Diabetes Mellitus (NDM) and 3) Congenital Hypoglycemia (CH).<\/p>\n

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MODY comprises at least 14 subtypes, of which MODY 1 and MODY 3 are the commonest forms. Patients with these forms of MODY are usually mistaken to have type 1 diabetes (insulin dependent diabetes) and prescribed lifelong insulin injections. However, if one studies the clinical profile of these patients, and more importantly, does a genetic test, it can be proved that they have MODY and not type 1 diabetes. The good news is that patients with MODY can stop insulin injections and be switched over to inexpensive sulphonylurea tablets. This can be life changing as far as the individual and the family are concerned.<\/p>\n

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Even more dramatic is the case of Neonatal Diabetes Mellitus (NDM)<\/strong> which is defined as onset of diabetes\u00a0 below. 6 months of age. These neonates are also usually diagnosed to have type 1 diabetes and asked to take insulin injections several times a day. \u00a0If genetic testing is done in these individuals and certain specific mutations are detected, the insulin injections can be stopped and they can be switched over to oral sulphonylurea treatment. This is nothing short of a miracle<\/strong>. Hundreds of such children have been referred to Dr. Mohan\u2019s Diabetes Spcialities Centre and the Madras Diabetes Research Foundation from all over India for genetic testing and many have been successfully converted to sulphonylurea tablets and were able to stop insulin injections completely.<\/p>\n

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Children with Congenital Hypoglycemia (CH)<\/strong> have the opposite condition of neonatal diabetes. From the time of birth, these babies have severe low sugar reactions. <\/strong>They may present with epileptic fits and other symptoms of low sugar. Many of them can be treated with a medicine called as \u2018Diazoxide\u2019, \u00a0while some have to undergo a partial removal of the pancreas (Pancratectomy). Again, in these neonates with CH, definite genetic mutations are present.<\/p>\n

 <\/p>\n

At Dr. Mohan\u2019s Diabetes Spcialities Centre and the Madras Diabetes Research Foundation, over the past several years, many cases of MODY, neonatal diabetes and congenital hypoglycemia have been successfully treated. Some of these patients were \u00a0available at the Press Conference to tell their story.<\/p>\n

\u00a0<\/strong><\/p>\n

Dr.V.Mohan<\/strong>, Chairman Dr. Mohan\u2019s Diabetes Specialities <\/strong>says, \u201cMore research is needed on monogenic forms of diabetes. We have seen a steady increase in children suffering from this form of diabetes over the last few years due to better awareness and detection. We are happy that the Indian Council of Medical Research (ICMR) has made MDRF, \u00a0the Coordinating Centre for the \u00a0\u2018National Monogenic Diabetes Study Group of India\u2019. This is the need of the hour and will surely help advance research in new avenues of treatment for the different kinds of monogenic diabetes like MODY and neonatal diabetes\u201d.<\/p>\n

Dr. Ranjit Unnikrishnan, Vice Chairman, DMDSC <\/strong>said,\u201dWith the advancement in technology, \u00a0today, by doing a genetic evaluation, it is possible to accurately diagnose all the monogenic forms of diabetes. This has great clinical significance because patients with monogenic forms of diabetes can be mistaken for type 1 diabetes and may be asked to take lifelong insulin injections. When diagnosed correctly, <\/em>these young children can be provided with effective treatments that will enable them to enjoy a fulfilling and normal life. \u201c<\/p>\n

\u00a0<\/strong><\/p>\n

The Indian Council of Medical Research (ICMR) <\/strong>has nominated the Madras Diabetes Research Foundation <\/strong>and Dr. Mohan\u2019s Diabetes Specialities Centre<\/strong> as the \u2018National Coordinating Centre<\/strong> for the \u2018National Monogenic Diabetes Study Group of India\u2019. <\/strong>Several top institutions, diabetologists and endocrinologists, including many prestigious medical colleges all over India, have consented to be members of \u00a0this study group.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u00a0 This move highlights the importance of evaluating Monogenic Diabetes \u00a0 Chennai, November, 2018 : As part of the World Diabetes Day 2018, Dr. Mohan\u2019s Diabetes Specialities Centre (DMDSC) conducted, a first of its kind press conference in Chennai to create awareness on the various forms of Monogenic Diabetes. Young patients with diabetes who are […]<\/p>\n","protected":false},"author":2,"featured_media":13811,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[31],"tags":[],"class_list":["post-13810","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"_links":{"self":[{"href":"https:\/\/www.faceinews.com\/index.php?rest_route=\/wp\/v2\/posts\/13810","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.faceinews.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.faceinews.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.faceinews.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.faceinews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=13810"}],"version-history":[{"count":1,"href":"https:\/\/www.faceinews.com\/index.php?rest_route=\/wp\/v2\/posts\/13810\/revisions"}],"predecessor-version":[{"id":13813,"href":"https:\/\/www.faceinews.com\/index.php?rest_route=\/wp\/v2\/posts\/13810\/revisions\/13813"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.faceinews.com\/index.php?rest_route=\/wp\/v2\/media\/13811"}],"wp:attachment":[{"href":"https:\/\/www.faceinews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=13810"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.faceinews.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=13810"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.faceinews.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=13810"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}